Our Mission

The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) is an international group of rheumatologists and immunologists with special interests in lupus who have been working together on lupus research since 1991. Our mission statement is:

Towards a better world for people with lupus through prevention and improved outcomes

Join us in our mission. We at SLICC, rely completely on the generosity and support of our donors and funders to continue our work.

SLICC developed the Damage Index – the only internationally accepted way of measuring the long-term effects of lupus and its treatment on the body. Without this index, it would be impossible to study those effects over time and compare them between different countries, geographies, and ethnic groups.

SLICC carried out the largest ever study of cancer in patients with lupus – this taught us that only some cancers are more likely to occur in patients with lupus and that the drugs commonly used to treat this disease do not significantly increase this risk of cancer.

But to continue our work, to answer the questions that patients with lupus are asking, we need to invest.

History & Objectives


Since its inception over 25 years ago, SLICC has evolved into a dynamic and expanding research group helping to promote lupus research and collaboration between scientific investigators. Over its history, SLICC has contributed to the development of multiple standardized outcome measures to better characterize lupus activity and damage as well as its response to varying treatments.

Current Activities

SLICC’s Research

SLICC is dedicated to generating new knowledge in the field of lupus, and translating these basic and clinical research discoveries into better health care practices and policies to help provide a healthier future for people diagnosed with lupus.

In 1998, the SLICC group established a longitudinal cohort of newly diagnosed patients with lupus (SLICC Inception Cohort) to better understand risk factors for atherosclerosis and metabolic syndrome, and characterize nervous system involvement.

Our current research activities are focused on atherosclerosis, nervous system involvement, lupus nephritis, and damage accrual, and their economic impact using the inception cohort. New initiatives include development of a pregnancy cohort and working group on microparticles as well as revision of the SLICC/American College of Rheumatology (ACR) Damage Index (SDI).


Organizational Structure

SLICC consists of a Board of Directors and 3 standing committees.

View Governing Body


SLICC is an international research organization with 54 members who, collectively, represent 43 academic medical centres across 16 countries and 5 continents.



May 22, 2019

A New Study Examines Cerebrovascular Events in Lupus Patients.

Stroke and transient ischemia are the most common cerebrovascular events in lupus patients, and a new study has found most of these occurrences can be attributed to lupus itself rather than other causes. Click here to find out more.

May 10, 2019

Dr. Dafna Galdman receives 2018 Distinguished Clinical Investigator Award

Congratulations to Dr. Dafna Gladman on receiving the 2018 American College of Rheumatology, Distinguished Clinical Investigator Award. Each year the American College of Rheumatology recognizes its members’ outstanding contributions to the field of rheumatology through an awards program.

Oct 19, 2018

Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study

Ustekinumab is a monoclonal antibody targeting interleukin (IL)-12 and IL-23 and is approved for the treatment of plaque psoriasis, psoriatic arthritis, and Crohn’s disease. IL-12 and IL-23 have been implicated in systemic lupus erythematosus. We aimed to assess the efficacy and safety of ustekinumab for the treatment of systemic lupus erythematosus in patients with moderate-to-severe disease activity despite conventional treatment.